Features | Your Skin Online https://yourskinonline.com Better Skin - Your Skin! Thu, 04 Feb 2021 21:43:29 +0000 en-US hourly 1 https://wordpress.org/?v=6.4.5 122115883 Vitamin E for Skin & Overall Health: Uses, Benefits & Contraindications https://yourskinonline.com/vitamin-e-for-skin-overall-health-uses-benefits-contraindications/ https://yourskinonline.com/vitamin-e-for-skin-overall-health-uses-benefits-contraindications/#comments Mon, 06 Aug 2018 16:54:42 +0000 https://yourskinonline.com/?p=1905

If you take a look at a few of the skincare products you currently own or use, you’ll probably find that it contains Vitamin E. It will either be listed as that, or as Tocopherol or Alpha-Tocopherol on the manufacturer’s ingredients list on the product packaging. It is typically included not only for its skincare benefits but also because it acts as a safe and natural stabilizer in beauty products which will help give them a longer shelf life.

What’s the story behind Vitamin E? Is it one of the unsung heroes of skin care and beauty?

What is Vitamin E?

Vitamin E is a fat soluble vitamin found in plant oils and in the leaves of many green vegetables. It is also known as an antioxidant which protects the body from free radicals. Typically there are eight different forms of naturally sourced Vitamin E. These are:

  • Alpha-tocopherol
  • Alpha-tocotrienol
  • Beta-tocopherol
  • Beta-tocotrienol
  • Gamma-tocopherol
  • Gamma-tocotrienol
  • Delta-tocopherol
  • Delta-tocotrienol.

Alpha-tocopherol is the most commonly known and used form of Vitamin E and is the only one that can reverse Vitamin E deficiency in those that need to take it for medical reasons.

Vitamin E is a nutrient and a powerful antioxidant and it has been used in serious, clinical dermatology for more than fifty years. There is serious scientific research that shows it can help with some common, but serious skincare concerns such as burns, scars and wounds.

It’s a key vitamin needed to build up good immunity and for healthy skin. The healthcare supplement market has seen a huge rise in the number of people taking it as an antioxidant in its own right. We need antioxidants in our diet not just for the good of our skin, but to help protect the cells in our body from free radical damage.

Why take Vitamin E?

Put simply, it can do absolutely no harm to use it topically in a skincare preparation. However, if you’re looking to it as a wonder cure, or preventative treatment to help guard against conditions like heart disease, cancer, stroke, Alzheimers or common conditions of the eye like cataracts then you might be disappointed to hear that scientific research into the benefits of this Vitamin are pretty lacklustre, with no clear benefits or gains from taking it.

Science has been able to establish that the only real benefits of taking a Vitamin E supplement are for people who are known to have a medically diagnosed deficiency in it. However, Vitamin E deficiency happens to be very rare – and only tends to crop up in people who suffer from serious digestive problems or conditions like cystic fibrosis. If you’re on a very low fat diet to lose weight, you may also find you’re deficient in this vitamin too.

Let’s take a look at the RDA of Vitamin E for essential good health and some of the sources you can get it from in your diet.

Vitamin E RDA in Milligrams and International Units

CHILDREN Aged 1-3 Years 6 mg/day (9 IU) CHILDREN Aged 4-8 Years 7 mg/day (10.4 IU)
CHILDREN Aged 9-13 Years
11 mg/day (16.4 IU) FEMALES Aged 14 Years and Onwards 15 mg/day (22.4 IU)
PREGNANT FEMALES 15 mg/day (22.4 IU) BREASTFEEDING FEMALES 19 mg/day (28.5 IU)
MALES Aged 14 Years and Older 15 mg/day (22.4 IU)

The amount suggested above are the upper intake guidelines, and the highest amount that people can take safely. However, if you have been diagnosed with a Vitamin E deficiency for any reason then a higher dose may be safely prescribed by a Doctor or other Healthcare Practitioner. Only ever take more than the recommended amount if you have been advised that it is safe to do so by a Doctor. Vitamin E is a fat soluble supplement and therefore it is always best to take it with food, and not on an empty stomach.

Which foods are rich in Vitamin E?

Many people get all the Vitamin E they need from the foods they eat in their diet. The best sources of this nutrient come from the following foods:

  • Vegetable oils
  • Green leafy vegetables, like spinach
  • Fortified cereals
  • Eggs
  • Nuts

Are there any risks from taking Vitamin E?

This is, on the whole, unclear as yet and not enough research has been undertaken. There are some studies which suggest that taking it long term (over a decade) has been linked to an increase in susceptibility to having a stroke. However, many doctors are coming round to the notion that it may have increased and long term health benefits to certain patients. More research is clearly needed in this field.

Alongside this, certain clinical trials have ascertained that patients who took Vitamin E (either synthetic or natural source) in doses of more than 400 IU per day increased their risks of dying from all causes. This risk increased even more if higher doses were given. Studies on people with cardiovascular problems suggested that people who suffered from diabetes or other cardiovascular diseases, and who took Vitamin E at the same dose (400 IU) had an increased risk of heart failure and heart failure-related hospitalization.

Pregnant women are advised against taking the supplement in the early stage of pregnancy, unless advised by a medical practitioner. A study found that women who took Vitamin E during the first eight weeks of their pregnancy had a 1.7 to 9 fold chance of their baby developing congenital heart defects. Another large scale study found that men who took a Vitamin E supplement alongside a multivitamin ended up with a significantly increased risk of developing prostate cancer.

Therefore many healthcare practitioners and health associations simply recommend that you get all the vitamin E you need from your diet and that if you are considering taking a supplement, you only do so under the guidance of a doctor.

Are there any side effects of taking Vitamin E?

Topical vitamin E can occasionally irritate the skin, if you are very sensitive. If you take it as a supplement and overdose this can cause nausea, headache, bleeding, fatigue, and other symptoms. If you take any other form of prescribed medication, in particular, blood thinners then it is important that you speak to a Doctor before you go ahead and take a supplement.

Vitamin E Benefits for Skin and Hair

The benefits of Vitamin E for skin and hair are as follows:

It’s a great protector for your skin

As it is an antioxidant, it’s known to fight free radicals. When it is used as a topical preparation for the skin it can help provide a barrier that fights skin damage caused by such issues as over exposure to the sun.

In a study that was carried out and published by the American Academy of Dermatology, scientists took two vitamins, Vitamin C and Vitamin E. On testing the two vitamins together and alone they found that together they offered excellent UV protection compared to just using them in isolation. They two work well on their own and are still recommended as better than nothing at all, but together they offered greater protection from the sun and reduced sunburn cell formation.

If you’re looking to improve your sun care regimen then there are plenty of chemical free sunscreens on the market which contain both Vitamin C and E. Additionally, applying Vitamin E creams, lotions or ointments onto skin that has been burned or sunburned can aid the skin’s recovery process.

Vitamin E Improves Dry Skin

Vitamin E is generally noted as being great at improving dry, flaky, itchy skin and skin conditions. You can smooth it into your elbows, knees, cuticles and over your lips to prevent dry, chapped skin. Some people even use small amounts of Vitamin E to seal the hair shaft after a blow dry or straightening treatment. It seals the cuticle of the hair down and prevents dryness.

You can also use it in the same way you might use coconut oil as a pre-shampoo treatment for critically dry hair. Warm a tablespoon full of the oil gently in the palms of your hands. Smooth it through the mid lengths and ends of your hair. Leave to sink in for at least twenty minutes, but for best results overnight. Then rinse, shampoo out and condition and style as normal.

Helps with scar healing

Vitamin E oil has the potential to help heal skin scars or the scarring from acne when applied topically.

There is to date, only one clinical study on this but it shows promising results. In 2010 the Journal of Plastic, Reconstructive & Aesthetic Surgery conducted a study on children who had undergone surgery. They had topical Vitamin E applied three times a day for thirty days after their operation.

The there control group were simply given a petroleum based cream to apply for the same amount of time. Results shows there were no children in the Vitamin E group who got scars. In the control group just under seven per cent got scars after six months had passed.

Can potentially help stop wrinkles forming

For those people looking to find natural ways to prevent wrinkles, Vitamin E is a good way of providing anti-aging to the skin. It can improve fine lines and wrinkles as it gives an antioxidant boost which helps prevent sun damage and also aid in skin cell turnover. It also works as a superb skin softening agent, decreasing dryness which in turn makes the sign of ageing less noticeable.

Help for your hair

We’ve already seen how Vitamin E can be used as a hair treatment, but it can also be used to massage the scalp to encourage hair growth and blood flow to the scalp itself. Some people will actually burst open a Vitamin E capsule and either apply that directly to the skin or use the contents to massage into their scalp and hair.

Using Vitamin E Oil as part of your skin and hair care regimen

If you’d like to experiment with using Vitamin E as a skin care preparation, then the best time to try it is at night as, because it is a fat soluble vitamin it can be thicker and greasier. If you’re opting to use pure oil then you need to apply it very sparingly to see good results. No more than one or two drops (unless your skin is critically dry).

Many people will simply take a Vitamin E capsule, gently cut or puncture it and apply the contents to their skin. You can buy Vitamin E oil from a bottle which you can use in the same way. The benefits of using pure Vitamin E oil is that you’re getting the purest concentration of the nutrient and this will do the best for your skin.

If you’re using it to help treat face concerns like fine lines, wrinkles or acne scars you can use the oil neat and smoothed onto the area of concern, or buy a specially formulated skin cream with Vitamin E in it. Alternatively you can turbo charge your existing moisturiser by adding in a drop or two of Vitamin E oil. Wheatgerm Oil is an excellent source of Vitamin E and can be used topically as a treatment.

If you’re looking to buy an good quality Vitamin E oil, look for one that is labelled ‘natural’ or as d-alpha-tocopherol. Check the ingredient label of the product and you’ll find that synthetically-made vitamin E oil is listed as all-rac-alpha-tocopherol or sometimes labeled as dl-alpha-tocopherol

Always store your Vitamin E, whatever you’re buying it for, in a cool, dark place.

Are there any contraindications to using Vitamin E?

You can safely apply it to your skin and hair, but it is always advisable to do a patch test first. Apply a small amount of the oil to the inside of your elbow and leave to dry, don’t wash this part of your skin for twenty four hours or so. If there is no redness or reaction, then you can safely apply this without worry.

It’s worth noting that even if you can’t tolerate it on your skin, you may still be OK to use it on the end of your hair or on your cuticles.

If you notice any redness, discomfort or burning after applying Vitamin E containing products, stop using them straight away and seek medical attention.

Resources & Further Reading

https://www.webmd.com/diet/supplement-guide-vitamin-e
https://draxe.com/vitamin-e-benefits/
https://www.healthline.com/health/all-about-vitamin-e
https://www.nhs.uk/conditions/vitamins-and-minerals/vitamin-e/
https://upload.wikimedia.org/wikipedia/commons/c/c3/Vitamin_E_%2831992676570%29.jpg
https://upload.wikimedia.org/wikipedia/commons/8/8d/Vitamina_E_%28suplemento%29_095.jpg
https://unsplash.com/photos/LL1vA5sUs6g

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Is Talcum Powder Safe or Not for Our Skin? https://yourskinonline.com/is-talcum-powder-safe-or-not-for-our-skin/ https://yourskinonline.com/is-talcum-powder-safe-or-not-for-our-skin/#comments Tue, 24 Jul 2018 20:38:49 +0000 https://yourskinonline.com/?p=1815

We all strive to be as ecologically sound and environmentally friendly as we can these days, especially when it comes to our beauty routines. What could be more natural than using talcum powder? It’s a product that has been used on babies, children and adults for many generations.

What does it consist of? We’re probably more familiar with one of it’s brand names ‘baby powder’ and it’s main constituent parts are magnesium, silicon and oxygen. Looking at those specific minerals, it appears to be pretty perfect. A natural product that can be used to help absorb excess moisture without drying the upper levels of the epidermis and doesn’t compromise hygiene or condition of the skin itself.

However, in recent years there have been a raft of reports in the press relating to how potentially unsafe talc could be, with stories of people who have potentially become ill after using it for many years.

The other side of the story is quite different, manufacturers of these products and health officials claim there is no danger to using talcum powder and we’re unlikely to become ill from repeated usage of it. Why is it getting such a bad press? Here, we investigate the two halves of the argument as to whether or not talcum powder is safe to use.

Talcum Powder – The Case For

Talcum powder has a long history of being used in consumer products, and it’s been added as an ingredient in a range of very varied cosmetic preparations. You may even have used it without knowing. If you have any of the following products in your personal care routine, check the ingredients label, as you’ll often find that talc is listed:

Products with Talcum Powder
Soap Shower Gels Bath Bombs Hand & Body Lotion
Feminine Hygiene Preparations Face Masks Toothpaste Deodorants

In makeup Talcum Powder will often appear as a filler in products like:

  • Blush
  • Bronzer
  • Face Powder
  • Foundation
  • Eye Shadow
  • Lipstick

If you turn the packaging over you’ll either see it listed as ‘talc’, ‘talcum powder’ or ‘cosmetic talc’.

Problems have arisen in recent years over claims that regularly using talcum powder can raise the risk of women developing cancer of the ovaries. Naturally, major cosmetic brands who use talc in their preparations have been keen to point out that it is very safe to use.

One of the main producers of this product is Johnson and Johnson and they have, after extensive studying, alongside the National Cancer Institute’s Physician Data Query Editorial Board, come to the conclusion that:

“The weight of evidence does not support an association between perineal talc exposure and an increased risk of ovarian cancer.”

This information is as recent as April 2017 and the mainstay of the argument in favor of continuing to use talc is that ‘no government health authority has concluded that talc can cause ovarian cancer’.

Clinical studies into the safety of Talc

Undertaking clinical study into anything which requires stringent medical research can be tricky, and the results difficult to interpret. Companies who are seeking to prove the efficacy and safety of cosmetic products will therefore use something called a prospective cohort study instead.

This is a type of study in which different groups of people are asked questions relating to risk factors and usage of certain products. They are then followed for a short period of time so that relevant data can be collected and analyzed.

To get a better understanding, over previous decades these sorts of studies have been used to understand links between smoking and lung cancer, or whether high cholesterol and heart disease are interconnected.

In terms of identifying any potential issues that correlate use of talcum powder with the chances of developing ovarian cancer, there are three major cohort studies that have been undertaken, involving just under two hundred thousand women and which have been running between six and twenty-four years. Here we’ll examine these studies and what they have found:

USA NHS Study

Of all the cohort studies into the issue of talc and female health, the US NHS (Nurses’ Health Study) is the largest that has ever been undertaken.

It is funded by the US Government and has been operational since 1976. It aims to look into risk factors for most major chronic diseases in women for the last forty-three years. Some of the results of this study have helped develop and improve hormone therapies for breast cancers and also to expose the links between smoking and instances of chronic heart disease in females.

The sector of the cohort study which examined the use of talc considered responses and reports from well over seventy-eight thousand women, each of them followed up for twenty-four years. These women were asked if they had ever regularly used talcum powder on either their genital area, their regular monthly sanitary protection or both.

Forty percent of women asked the questions answered in the affirmative and were put into a ‘Talc User Group’. This equates to just under thirty-two thousand women. For the entire period of the study, these women who used talc regularly showed no overall increase in the risk of contracting ovarian cancer, to the women who did not use talc or talc products. There was also no difference to risk whether the women were regular, or occasional users of talcum powder.

The WHI Study

In 1991 The Women’s Health Initiative (WHI) was established by the USA National Institutes of Health, in order to study the health, wellbeing and lifestyles of postmenopausal women. They too carried out a cohort study on talc use and risk of contracting reproductive cancers.

The WHI Study involved some sixty-one thousand women. Of this group, over fifty percent admitted to using talcum powder on the same areas mentioned in the US NHS study.

These women were followed between the years 1993 and 2012. It was found that of well over thirty-two thousand women followed, there was again, no overall increase in the risk of contracting female reproductive cancers due to use of talcum powder.

The Sister Study

Between the years 2003-2009, the Sister Study was carried out, in conjunction with the National Institutes of Health. In enrolled over forty-one thousand women in the USA and Puerto Rico, who were aged between thirty five and seventy four. The other main caveat of the study was that any woman enrolled had to have a sister or half-sister who had been diagnosed with breast cancer already.

This study went a step further in that it also included analysis of participants to identify any potential associations between talc use, douching and female reproductive cancers. In the six year study, forty one thousand women were questioned. Of those, just under six thousand women said they regularly used talc or douched. These six thousand women, by the end of the cohort study showed no increased risk of contracting ovarian cancer from using talc. There was a slight increased risk of developing such carcinoma if the women douched.

These large scale studies have shown, often over long periods of time, that there is little risk to women who might use talc on a regular basis, to go on to develop female reproductive cancers.

However, stories and reports in the press have always persisted. It’s now time to look at the case against talc and whether it has any merit.

Talcum Powder – The Case Against

Whilst we’ve seen incontrovertible evidence in the form of cohort studies that claim talcum powder is totally safe to use there are some scientists who have been warning about the potential dangers it poses for some fifty years now.

Aside from this, in the last two years, cosmetic giant Johnson and Johnson has paid out more than $700 million dollars for lawsuits surrounding the use of talcum powder and the increased risk of contracting female reproductive cancers.

It seems some of the issue with concerns regarding the safety of talcum powder stems from the fact that although it’s a natural product, it is mined in close proximity to asbestos. Which although also a naturally occurring substance, is known to have carcinogenic effects.

The FDA have stated that in order “to prevent contamination of talc with asbestos, it is essential to select talc mining sites carefully and take steps to purify the ore sufficiently.” The FDA also consider it unacceptable for any talc being used for >cosmetic purposes to be contaminated with asbestos. All well and good, and as it should be. However, at the current time of writing there is still no federal mandate which allows for the testing and safety of ingredients and cosmetics before they wind up on the shelves of drug stores and grocery stores.

FDA 2009 Study into Talc

Nine years ago in 2009, the FDA asked a group of nine talc suppliers to take part in a study they were conducting. In order to do so, these nine participants had to send in samples of their talc. Of the nine requests, it seems only four suppliers complied. In the meantime, thirty-four different cosmetic products containing talc were purchased in the Washington DC area. These were then sent to labs, to be tested for asbestos contamination.

Although the test results showed no trace of contamination, the FDA made moves to suggest that the findings were flawed as only four suppliers gave samples and only thirty-four products were tested. The FDA stated that this does not prove that all talc containing products sold in the USA are free from any form of asbestos contamination.

Talcum Powder Cancer Scare Stories

Talc Linked to Increased risk of Ovarian Cancer

The American Cancer Society say there are varied studies which link talcum powder to an increased risk of ovarian cancer. The claim that if a woman applies any product containing talc to her genital area, that talc particles can travel through the vagina, up into the uterus, fallopian tubes and finally to the ovaries.

Indeed, the first study suggesting that there was any sort of connection between the two, was released forty-seven years ago in 1971. Talc particles had been found in ovarian tumors in humans. Nine years later in 1982, another study put the same link forward.

Two years ago, in 2016, a study published in Epidemiology looked at the relationship between ovarian cancer and use of talc on the genitals. A study group of just over two thousand women with ovarian cancer and the same number of women without were used as control groups.

Results from the data showed that use of talc on the genitals raised the risk of contracting reproductive cancers by thirty three percent. Contrary to the studies seen earlier, the risk increased the more women used talcum powder. In a study of more than a thousand African American women, the results of which were published in Cancer Epidemiology, Biomarkers and Prevention, found that talcum powder use was likely for over sixty percent of the women studied – all of whom had ovarian cancer. This implied there was an association between the two.

Talcum Powder and the effects on the lungs

We’ve so far merely examined the effects talc might or might not have on the health of the reproductive organs. However, we’ve yet to consider the effects on the health of breathing it in.

Inhaling talcum powder directly is not seen as being connected to the development of lung cancer, there are some studies which have shown there may be a slightly increased risk of contracting lung cancer and other respiratory tract illnesses among the people who mine for talc. However, this seems to be solely related to the different forms of asbestos that can contaminate the talcum powder itself.

Three years ago, in 2015, research published in Occupational and Environmental Medicine noted that there was an increase in mortality from lung cancer amongst those people who mined talc. The data was inconclusive however, as it could not be adjusted to measure the effects of talc only, and it was not clear whether miners had also been exposed to other carcinogens. There is a type of lung condition named pulmonary talcosis, which although a relatively rare illness is caused primarily by inhaling talc due to occupational exposure.

In the British Medical Journal, a report highlights the case of a twenty four year old mother who routinely inhaled cosmetic grade talcum powder. A decade on from this, she developed pulmonary talcosis. The main symptoms of this are irritated airways, chronic coughing and problems with breathing.

Breathing issues after inhaling talc are sometimes present in infants and children, too. In the USA, poison control center reports have shown that there are incidences of small babies and infants inhaling talc during diaper changes. This inhalation can dry the mucous membranes and affect breathing. If you believe your health has been compromised by baby powder, you may wish to consult with an attorney who is experienced with talcum powder lawsuit litigation and fighting for your rights.

One particularly severe case also published in the British Medical Journal highlighted that of a three month old baby who had talcum powder spilt on his face. Having ingested some of it, he immediately vomited and had to be admitted to hospital a short time later with breathing difficulties. Once his condition had been stabilised he reportedly vomited up all the talcum powder he had ingested, and his condition improved.

In conclusion

As with anything of this nature, that has the ability to affect your life, or your health, it is better to weight up the evidence on an individual basis. It’s clear there are arguments on both sides that offer some compelling evidence for and against the usage of talc as a consumer product. Whilst it is true that there is some anecdotal evidence that talc can potentially cause reproductive tumors or other conditions which might affect the lungs, some of the work on those studies is now over forty years old, and science has moved on a great deal in that time. The cohort studies, carried out over many decades and on a very large scale, might provide the best source of sensible information to help you make your mind up.

It’s also clear the FDA need to step up and introduce better methods of screening and testing cosmetic products containing talc, and also, perhaps on a more general level too – to ensure greater levels of transparency and public safety. In the meantime, if you are feeling concerned, the best course of action is to speak to a healthcare professional, especially if you are worried you might be experiencing some of the symptoms concurrent with reproductive cancers.

There are always alternatives to talcum powder on the market, and some cosmetic brands are now marking their products as being ‘talc free’ in a bid to placate worried consumers. Look for those on the shelves in department stores.

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The Surprising Ways Smoking Affects Skin Health https://yourskinonline.com/the-surprising-ways-smoking-affects-skin-health/ https://yourskinonline.com/the-surprising-ways-smoking-affects-skin-health/#respond Tue, 22 May 2018 14:58:42 +0000 https://yourskinonline.com/?p=1192

Is there a body system that is not affected by smoking? The short answer is no, especially when it comes to the skin. The CDC reports that 16 million Americans are living with some form of ailment related to smoking. Among these ailments is the damage smoking causes the skin. Internally and externally, the skin is damaged over time through nicotine use. Often, people want to look better after quitting nicotine for good and will start by healing the skin. Omitting nicotine followed by a natural beauty regime often reverses much of the skin damage caused by smoking, even after decades.

How Smoking Harms Skin

Nicotine causes bags under the eyes through a lack of sleep. Researchers are not sure why smokers sleep worse than non-smokers, but it is believed that it has something to do with the nicotine withdrawal overnight. Wrinkles also appear as the nicotine prevents blood flow through the body. Necessary oxygen to help keep the skin’s elasticity is reduced, causing the skin to sag early. The same lack of oxygen and heightened carbon monoxide zaps nutrients from the skin. The healthy glow is replaced by a gray appearance. The body begins healing immediately after quitting smoking, including the skin, but natural remedies help improve the outer appearance faster.

Moving the Process Along Faster

Getting rid of wrinkles, eye bags, and replenishing that healthy glow feels great when it’s done naturally. Nature helps heal the skin faster as well, as natural products give the skin what it needs most – healing without additives. Aloe vera is a wonderful product for helping reduce wrinkles. The gel from the plant is used to help bring back skin’s elasticity. Lemon and vinegar mixtures have helped remove age spots, and cucumbers on the eyes have helped reduce bags. Cold potatoes, chilled milk, and Vitamin E oil also help ease the rings under the eyes.

Keep the rest of the vegetables for a salad that’s rich in vitamins, as these need to be replaced internally to help bring back increased blood circulation. Wash the face with raw honey and follow with coconut oil to bring back a touchable, enticing look. Search for products that have these natural ingredients to help with ease of application and a faster return to gorgeous skin.

Smoking harms the skin inside and out. After quitting, pamper the skin to return to a younger look and a better feel. As the body rebuilds itself, the appearance also improves almost immediately. Help the skin with natural remedies that are guaranteed to work.

Sources & Further Reading:

https://unsplash.com/photos/8UVCrxjpC_M
https://unsplash.com/photos/zXQdgHr2KIw
https://unsplash.com/photos/YXyjjg32ei0
https://www.medicaldaily.com/its-not-smoke-its-nicotine-e-cigarettes-may-damage-arteries-265498
https://www.luxurymedical.co.uk/financial-quit-smoking-timeline/
https://ods.od.nih.gov/factsheets/VitaminE-HealthProfessional/

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